I'm sure the new owners & hopefully, new management team, will have some thoughts; typically CZ builds what the client base is interested in; I'm hoping for some SAA 5.5", B-CCH in 44WCF or .357 and a NM built along the lines of the 9MM & .40 Comp pistols but in .45ACP & SA, of course; none of that DA/SA stuff..Colt's catalog is getting thicker and thicker; especially when you look at their "custom shop".
For regular production guns, I can think of two that seem like no-brainer's to me since they're already most of the way there. A blued Python, and a .22 Diamondback.
For the custom shop...
One "retro" 1911 Colt has never done are the pre-War Super Match guns...That would be a cool retro to make.